Abstract

Author:
Rashok Khanal, Subir Singh, Alina Subedi

Doi: 10.26480/mahj.01.2024.12.14

This is an open access article distributed under the Creative Commons Attribution License CC BY 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

Ascites syndrome (AS) remains a significant challenge in the poultry industry, causing substantial financial losses globally despite extensive research efforts. This review highlights the multifactorial nature of AS, emphasizing its complex interplay between genetics, environment, and management practices. Intense selection for rapid growth and enhanced feed conversion efficiency in modern broiler lines has led to metabolic disorders, including AS. The syndrome, characterized by pulmonary hypertension and right ventricular hypertrophy, results from an imbalance between oxygen demand and supply, particularly evident in cold climates or when birds are fed high-nutrient diets. The partnership between primary breeders and integrators is crucial for disease control, necessitating the selection of genetic traits that confer resistance to AS while optimizing animal welfare and productivity. Additionally, historical instances of AS outbreaks, such as the “toxic fat syndrome,” underscore the need for continued vigilance and global collaboration in AS research and management. Despite advancements, AS remains a persistent challenge, highlighting the ongoing need for comprehensive approaches to disease prevention and control in poultry production systems.